Mass General Cancer Center Grand Rounds
Grand Rounds
Mass General Cancer Center Grand Rounds is a CME accredited weekly seminar series. Cutting edge topics, case studies and conference highlights will be presented.
Fall 2023 - Spring 2024 Grand Rounds
Time: Thursdays, 12:00 PM–1:00 PM
Location: Yawkey 4820
Course Director: Colin D. Weekes, MD, PhD
The Mass General Cancer Center Grand Rounds program has emerged as a premiere oncology conference in Boston. This program provides an opportunity for Mass General professional staff and fellows to learn from national and international leaders and innovators in cancer treatment and research. This year’s theme for the series is Women in Cancer.
Grand Rounds offers CME credit, and is structured as a 45-minute lecture followed by 15 minutes of discussion and interaction. Please see below to view the weekly topics and presenters.
Outside of Mass General and interested in viewing the Grand Rounds? Click here to access our new Mass General Cancer Center Grand Rounds subscription available to the public.
Spring 2024 Grand Rounds Schedule
January 4, 2024
ASH Update
Classical Heme (Jonathan Carlson, MD, PhD)
Leukemia (Rupa Narayan, MD)
Lymphoma (Jacob Soumerai, MD)
Myeloma (Diana Cirstea, MD)
BMT (Richard Newcomb, MD)
Cell Therapy (Mark Leick, MD)
January 11, 2024
Integrating Clinical and Laboratory Research to Identify Mechanisms of Response and Resistance to Immune Checkpoint Therapy
Padmanee Sharma, MD, PhD
MD Anderson Cancer Center
January 18, 2024
From the Ether Dome to Seldin Plaza: My Path in Renal Cell Carcinoma
Tian Zhang, MD
UT Southwestern Medical Center
January 25, 2024
Can’t Stop, Won’t Stop: The Development of New Therapies, and New Trialists, Toward a Future of Cure
Janice Mehnert, MD
NYU Langone Health
February 1, 2024
From Trailblazers to Leaders: Role of Women As Division Chiefs
S. Gail Eckhardt, MD, FASCO
Baylor College of Medicine
Merry Markham, MD, FACP, FASCP
University of Florida Health
February 8, 2024
Advocacy in Oncology: Connecting What Matters with Our Science and Care
Pamela Kunz, MD
Yale School of Medicine
February 29, 2024
Brain Metastases of Breast Cancer
Patricia Steeg, PhD
National Institutes of Health
March 7, 2024
Gastric Cancer Program: Innovations and Advances
Vivian Strong, MD, FACS
Memorial Sloan Kettering Cancer Center
March 14, 2024
Rethinking Radiation Oncology Using HPV Driven Oropharyngeal Carcinoma as a Model
Nancy Lee, MD, FASTRO
Memorial Sloan Kettering Cancer Center
March 21, 2024
Bridging the GAP While Shattering Ceilings
Rachna Shroff, MD, MS, FASCO
University of Arizona Cancer Center
March 28, 2024
Porphyria: New Therapies and Research
Rebecca Karp, MD
Massachusetts General Hospital
Amy Dickey, MD, MSc
Massachusetts General Hospital
April 4, 2024
DEI as a Competitive Advantage
Clifton David Fuller, MD, PhD
MD Anderson Cancer Center
April 11, 2024
Catch Me If You Can: Resistance to CART Immunotherapy
Marco Ruella, MD
University of Pennsylvania
April 25, 2024
Treating AML in 2024: Individualizing Treatment Approaches with Novel Therapies
Courtney DiNardo, MD, MSCE
MD Anderson Cancer Center
May 2, 2024
ACS-IRG Scholars
Shadi Abdar Esfahani, MD, MPH
Massachusetts General Hospital
Jamie Jacobs, PhD
Massachusetts General Hospital
Julie Miller, MD, PhD
Mass General Cancer Center
Gary X. Wang, MD, PhD
Massachusetts General Hospital
May 9, 2024
Circulating tumor DNA analysis for non-invasive detection of cancers
Max Diehn, MD, PhD
Stanford University
May 16, 2024
State of Cancer: National Efforts to Ensure Health Equity For All Americans
Elizabeth Jaffee, MD
Johns Hopkins Medicine
May 23, 2024
Clinical Pathologic Conference: NEJM Case Records of the MGH: A 59-year-old woman with a breast mass
Bayan Alzumaili, MD; Rebecca Kwait, MD; Daniel Soto, MD; Sahar Shahamatdar, MD, PhD; Janice Thai, MD; Seth Wander, MD, PhD; Lori Wirth, MD
Massachusetts General Hospital
Fall 2023 Grand Rounds Schedule
September 7, 2023
The Chabner Pioneers in Oncology Lectureship – Precision Medicine for Primary and Metastatic Brain Tumors: From Bench to Bedside (and Back to Bench)
Priscilla Brastianos, MD
Mass General Cancer Center
September 21, 2023
Junior Scientist Lectures
Targeted Approaches to Treatment of Pleural Mesothelioma: Are We There Yet?
Ibiayi Dagogo-Jack, MD
Mass General Cancer Center
Gut Bacteria Illuminate a Mechanistic Strategy for Cancer Immunotherapy
Francesca Gazzaniga, PhD
Massachusetts General Hospital
September 28, 2023
Structure and Function of Mammalian SWI/SNF Chromatin Remodeling Complexes in Cancer
Cigall Kadoch, PhD
Dana-Farber Cancer Institute
October 5, 2023
Novel Therapeutics in Gynecologic Cancers
Roisin O’Cearbhaill, MD
Memorial Sloan-Kettering Cancer Center
October 12, 2023
Women in Cancer: Navigating the Glass Ceiling
Lisa Butterfield, PhD
University of California San Francisco
Kornelia Polyak, MD, PhD
Dana-Farber Cancer Institute
Noopur Raje, MD
Mass General Cancer Center
October 26, 2023
Lippard Lecture: Defining and Exploiting Tumor-Host Interactions
Christina Curtis, PhD, MSc
Stanford University
November 9, 2023
Achieving Success as A Square Peg in the Round Hole of Academic Medicine
Jennifer Temel, MD
Mass General Cancer Center
November 30, 2023
Female Participant Engagement in Cancer Research: Sample Programs from the Field to a Pandemic
Lourdes Baezconde-Garbanati, PhD
University of Southern California
December 7, 2023
The Dobbs Decision: Implications for Women’s Health and Cancer Care
Lisa Barroilhet, MD
University of Wisconsin School of Medicine and Public Health
December 14, 2023
Targeted Therapy for Premenopausal Early Breast Cancer: A 100 Year Old Strategy
Sandra Swain, MD
Georgetown University Medical Center
Previous Grand Rounds
Spring 2023
January 5, 2023
ASH Update
Anem Waheed, MD, MPH
Mass General Cancer Center
Matthew Frigault, MD
Mass General Cancer Center
Yi-Bin Chen, MD
Mass General Cancer Center
Amir Fathi, MD
Mass General Cancer Center
Andrew Yee, MD
Mass General Cancer Center
January 12, 2023
Learning the Rules of Human Tumor Immunity
Nir Hacohen, PhD
Director, MGH Center for Cancer Immunotherapy
Center for Cancer Research
Professor of Medicine, Harvard Medical School
Senior Member, Broad Institute
January 19, 2023
Junior Scientist Lecture
Evaluating Novel Cancer Therapeutic Strategies Using Living Tumor Biopsies
Russell Jenkins, MD, PhD
Principal Investigator, Mass General Research Institute
Assistant in Medicine, Mass General Cancer Center
Assistant Professor, Harvard Medical School
Programming T Cell Exhaustion: Lessons from Chronic Viral Infection
Debattama Sen, MD
Principal Investigator
Mass General Cancer Center Center for Cancer Research
Assistant Professor, Harvard Medical School
January 26, 2023
Improving Response to Immune Checkpoint Inhibitor Therapy Through Solving the Underpinnings of Immune-Related Adverse Events
A. Chloe Villani, PhD
Assistant Investigator, Center for Immunology and Inflammatory Diseases
Mass General Cancer Center Center for Cancer Research
Assistant Professor, Harvard Medical School
February 2, 2023
2022 Assembly Award Winner Lecture: Targeting TBK1 to Overcome Resistance to Cancer Immunotherapy
Russell Jenkins, MD, PhD
Principal Investigator, Mass General Research Institute
Assistant in Medicine, Mass General Cancer Center
Assistant Professor, Harvard Medical School
February 9, 2023
Tissue-Based Immune Profiling and Pan-Tumor Pathologic Response Signatures
Janice Taube, MD, MSc
Director, Division of Dermatopathology
Professor of Dermatology
Johns Hopkins Medicine
February 16, 2023
Clinical Pathologic Conference: A 57-Year-Old Woman with Melanoma and Fever
Jiyoon Kang, DO
Massachusetts General Hospital
Matthew Meizlish, MD, PhD
Massachusetts General Hospital
Amir Mohareb, MD
Massachusetts General Hospital
Kam Montazeri, MD
Mass General Cancer Center
Stuti Shroff, MBBS, PhD
Massachusetts General Hospital
March 2, 2023
Cell Cycle Checkpoint Defects as Targets for Cancer Therapy: From Bench to Bedside
Kelly Hunt, MD, FACS, FSSO
Professor and Chair, Department of Breast Surgical Oncology
MD Anderson Cancer Center
March 16, 2023
Genetics, Immunobiology and Targeted Therapy of Hodgkin Lymphoma
Margaret Shipp, MD
Douglas S. Miller Chair in Lymphoma
Director, DF/HCC Lymphoma Research Program
Dana-Farber Cancer Institute
Professor of Medicine, Harvard Medical School
March 30, 2023
Immunotherapy for the Treatment of Acute Leukemias: Fake News?
John DiPersio, MD, PhD
Virginia E. and Sam J. Golman Professor in Medicine
Director, Center for Gene and Cellular Immunotherapy
Washington University School of Medicine in St. Louis
April 6, 2023
Progress in Immunotherapy for Breast Cancer
Leisha Emens, MD, PhD
Senior Vice President, Translational Research
Ankyra Therapeutics
April 20, 2023
Creating a Culture of Inclusion
Karen Winkfield, MD, PhD
Executive Director, Meharry Vanderbilt Alliance
Ingram Professor of Cancer Research
Professor of Radiology Oncology, VUMC
Professor of Medicine, Meharry Medical College
April 27, 2023
Neoadjuvant Immunotherapy for Resectable Lung Cancer
Patrick Forde, MBBCh
Co-Director, Division of Upper Aerodigestive Malignancies
Director, Thoracic Oncology Research Program
Bloomberg-Kimmel Institute for Cancer Immunotherapy
Johns Hopkins University
May 4, 2023
Cancer Immunotherapy, Shared Immune Escape and the Age of Engineering
Daniel Chen, MD, PhD
Founder, Engenuity Life Sciences
May 11, 2023
Normalizing the Tumor Microenvironment to Improve Immunotherapy of Cancer: Emerging Insights and Strategies
Rakesh Jain, PhD
Director, Steele Laboratory
Massachusetts General Hospital
A. Werk Cook Professor of Radiation Oncology
Harvard Medical School
May 18, 2023
CPC: A 45 Year-Old Female with Metastatic Triple-Negative Breast Cancer
Baris Boyraz, MD, PhD
Massachusetts General Hospital
Kevin Oh, MD
Massachusetts General Hospital
Karen Rodriguez, MD
Massachusetts General Hospital
Neelima Vidula, MD
Mass General Cancer Center
Alexandra Wong, MD
Massachusetts General Hospital
May 25, 2023
A Regulator’s Perspective on Endpoints Supporting Immuno-Oncology Approvals
Marc Theoret, MD
Deputy Director
Oncology Center of Excellence
U.S. Food and Drug Administration
Fall 2022
September 15, 2022
Leveraging Opportunities to Facilitate Inclusive Cancer Drug Development
Lola Fashoyin-Aje, MD, MPH
Deputy Division Director
Associate Director, Science & Policy to Address Disparities
Oncology Center of Excellence
FDA
September 22, 2022
ACS-IRG Scholar Presentations
The MGH Catch Project: Improving Community Access to Colon Cancer Screening
Adjoa Anyane-Yeboa, MD, MPH
Massachusetts General Hospital
An Omics Approach to Drug Discovery
Liron Bar-Peled, PhD
Mass General Cancer Center
CAR Talk: What Clinicians Say and Patients Understand about Chimeric Antigen Receptor T-cell (CAR-T) Therapy
Tejaswini Dhawale, MD
Mass General Cancer Center
Spatial Transcriptomics of HCC Reveals Distinct Vascular Neighborhoods
Joseph Franses, MD, PhD
Mass General Cancer Center
Intermediate States in Pancreatic Cancer Tumorigenesis Inferred by Single-Nucleus RNA-Sequencing
William Hwang, MD, PhD
Massachusetts General Hospital
September 29, 2022
Lymphocytes as a “Living Drug” for the Treatment of Cancer
Steven A. Rosenberg, MD, PhD
Chief, Surgery Branch
National Cancer Institute
October 6, 2022
Extending Immunotherapy Combinations in Gastroesophageal Cancer: How, What and When?
Ian Chau, MD, FRCP
Department of Medicine
Royal Marsden Hospital
October 13, 2022
New Considerations for Immunotherapy in Sarcoma
Seth M. Pollack, MD
Director of the Sarcoma Program, Lurie Cancer Center
Steven T. Rosen Professor of Cancer Biology
Associate Professor, Department of Medicine (Hematology and Oncology)
Northwestern University Feinberg School of Medicine
October 27, 2022
Kidney Cancer: Bench to Bedside and Back
James Brugarolas, MD, PhD
Director, Kidney Cancer Program
UT Southwestern
November 3, 2022
Debate: Adjuvant/Neoadjuvant Immune Checkpoint Inhibitor Therapy
Rodabe Amaria, MD
Associate Professor, Department of Melanoma Medical Oncology
Director of Melanoma Clinical Research and Early Drug Development
The University of Texas MD Anderson Cancer Center
Jeffrey Weber, MD, PhD
Deputy Director
Laura and Isaac Perlmutter Cancer Center
Professor of Medicine
NYU School of Medicine
Paul Chapman, MD
Attending Physician
Memorial Sloan Kettering Cancer Center
Professor of Medicine
Weill Medical College and Graduate School of Medical Sciences of Cornell University
November 10, 2022
TLR9 Agonists in Melanoma and Other Cancers: Current Development, Next Steps
Diwakar Davar, MD
Assistant Professor of Medicine
Medical Oncologist/Hematologist
UPMC
November 17, 2022
Lippard Lecture: Heterogeneity of Breast Cancer Across Diverse Populations
Olufunmilayo Olopade, MD, FACP
Walter L. Palmer Distinguished Service Professor of Medicine
Professor of Human Genetics
Director, Center for Clinical Cancer Genetics and Global Health
UChicago Medicine
December 1, 2022
The Chabner Pioneers in Oncology Lectureship: Translating Aging Biology Into Patient Care
Norman Sharpless, MD
Former Director, NCI
December 15, 2022
Immune Related Adverse Events: Discussion of Mechanisms and Models for Discovery
Arlene Sharpe, MD, PhD
George Fabyan Professor of Comparative Pathology
Chair, Department of Immunology
Co-Director, Evergrande Center for Immunologic Diseases
Harvard Medical School
Stephen Elledge, PhD
Gregor Mendel Professor of Genetics
Department of Genetics, Harvard Medical School
Division of Genetics, Brigham & Women’s Hospital
Spring 2022
January 6, 2022
ASH Update
Rupa Narayan, MD
Mass General Cancer Center
Connor Johnson, MD
Mass General Cancer Center
Anem Waheed, MD
Mass General Cancer Center
Matt Frigault, MD
Mass General Cancer Center
Andrew Yee, MD
Mass General Cancer Center
January 13, 2022
Junior Scientist Lecture
Looking Beyond the Marker: Pharmacologic and Immunotherapeutic Targeting of MUC16 (CA-125) Positive Gynecologic Cancers
Oladapo Yeku, MD
Mass General Cancer Center
Epidemiology and Prognostic Implications of Cutaneous Immunotherapy Toxicities
Eugene Semenov, MD
Massachusetts General Hospital
January 20, 2022
Confronting Inequity in Modern Therapy for Rare Melanomas
Alexander Shoushtari, MD
Memorial Sloan Kettering Cancer Center
January 27, 2022
Advancing Therapies for Children and Adults with Rare Solid Tumors or Genetic Tumor Predisposition Syndromes
Brigitte Widemann, MD
National Institutes of Health
February 3, 2022
2021 Assembly Award Winners and Lectureship
Safety and Immunogenicity of SARS-CoV2 Vaccines in Patients with Cancer
Justin Gainor, MD
Mass General Cancer Center
Clinical Resistance to KRAS Inhibition
Ryan Corcoran, MD, PhD
Mass General Cancer Center
February 10, 2022
Turning on Apoptotic Switch in Leukemia: BCL-2 and Beyond
Amir Fathi, MD
Mass General Cancer Center
Marina Konopleva, MD
MD Anderson Cancer Center
February 17, 2022
Clinical Pathologic Conference: A 66-Year-Old Man with Progressive Dyspnea and Neck Swelling, and a Lung Mass
Jennifer Temel MD – Medical Oncology
Katie Keane, MD - Radiation Oncology
David Dudzinski, MD - Cardiology
Subba Digumarthy, MD - Radiology
Colleen Keyes, MD - Pulmonary
Daniel Shepherd, MD - Pathology
Massachusetts General Hospital
March 3, 2022
Leadership Toolbox for Faculty Development Strategies to Enhance Diversity within the Profession
Charles Thomas, Jr., MD
Dartmouth-Hitchcock Norris Cotton Cancer Center
March 10, 2022
Engineering CAR-T Cells: Combating Tumor Resistance and Relapse
Renier Brentjens, MD, PhD
Roswell Park Comprehensive Cancer Center
March 17, 2022
Informing Race/Ethnicity Modeling for Colorectal Cancer Screening
John Carethers, MD
University of Michigan
March 24, 2022
The Race Between Immunity and Ovarian Cancer: How Tryptophan Metabolism Shapes the Outcome
Adekunle Odunsi, MD, PhD
University of Chicago
March 31, 2022
Senior Fellows Lecture
Interrogating the Immunogenicity of SARS-CoV-2 Vaccines in Chronic Lymphocytic Leukemia
Erika Haydu, MD, PhD
Fellow in Hematology/Oncology
Mass General Cancer Center / Dana-Farber Cancer Institute
Improving Outcomes for Hospitalized Patients with Advanced Cancer
Daniel Lage, MD, MSc
Fellow in Hematology/Oncology
Mass General Cancer Center / Dana-Farber Cancer Institute
Decoding the Rules of Pancreatic Cancer Plasticity and Immune Regulations
Arnav Mehta, MD, PhD
Fellow in Hematology/Oncology
Mass General Cancer Center / Dana-Farber Cancer Institute
April 14, 2022
Personalizing Care for Older Adults with Cancer
Heidi Klepin, MD
Wake Forest School of Medicine
Lisa Newman, MD, MPH
Weill Cornell Medicine
April 28, 2022
The Business of Cell Therapies for Cancer
James Economou, MD, PhD
University of California Los Angeles
Raymond Osarogiagbon, MD
Baptist Cancer Center
May 12, 2022
ACS IRG Scholars
Raj Gopal, MD, PhD
Massachusetts General Hospital
Daniel Hall, PhD
Massachusetts General Hospital
Andrew Liss, PhD
Massachusetts General Hospital
Erica Shenoy, MD, PhD
Massachusetts General Hospital
Eric Wehrenberg-Klee, MD
Massachusetts General Hospital
May 19, 2022
Clinical Pathologic Conference: A 22-Year-Old Female with Abdominal Pain
Baris Boyraz, MD, PhD
Massachusetts General Hospital
Sophia Kamran, MD
Massachusetts General Hospital
Allison Kimball, MD
Massachusetts General Hospital
Philip Saylor, MD
Mass General Cancer Center
Madeleine Sertic, MBBCH, BAO
Massachusetts General Hospital
Fall 2021
September 23, 2021
Industry Roundtable: A Conversation About Cancer Equity
Ruma Bhagat, MPH
Senior Science Leader Global Health Equity Strategy
Genentech, Inc.
Patrice Matchaba, MD
Global Head of Corporate Responsibility
Novartis US
Coleman Obasaju, MD, PhD
Senior Medical Director - Oncology
Eli Lilly and Company
David Windsor
Clinical Trials Diversity Ops Lead for Oncology
Pfizer
September 30, 2021
Keynote Address: The Impact of Population and Tumor Heterogeneity in Cancer Genome Science
John D. Carpten, PhD
Professor and Chair of Translational Genomics
Director, Institute of Translational Genomics
Royce and Mary Trotter Chair in Cancer Research
Department of Translational Genomics
Keck School of Medicine of USC
October 7, 2021
DNA Damage Repair Deficient Pancreas Cancer
Talia Golan, MD
Head of Sheba Pancreatic Cancer Center
Sheba Medical Center, Tel HaShomer
October 14, 2021
Clinical Pathologic Conference: A 29-Year-Old Woman with Jaundice and Chronic Diarrhea
Jon Dubois, MD
Medical Oncologist
Mass General Cancer Center
Jennifer Wo, MD
Radiation Oncology
Massachusetts General Hospital
Avinash Kambadakone, MD
Radiology
Massachusetts General Hospital
M. Lisa Zhang, MD
Pathology
Massachusetts General Hospital
October 21, 2021
Utilizing Underlying Tumor Biology to Guide Immunotherapy Drug Development in Sarcoma, One Subtype at a Time
Sandra D’Angelo, MD
Associate Attending Physician
Memorial Sloan Kettering Cancer Center
October 28, 2021
Patient-Centered Care in the Precision Oncology Era
Laura Petrillo, MD
Palliative Medicine
Mass General Cancer Center
November 4, 2021
The Chabner Pioneers in Oncology Lectureship: Getting to the Root of Cancer Health Disparities: A Journey to Health Equity
Michele K. Evans, MD
Deputy Scientific Director & Chief
Health Disparities Research Section
National Institute on Aging
National Institutes of Health
November 11, 2021
Immune-Related Toxicities: Diversity in Clinical Research and Innovation
Jarushka Naidoo, MB, BCH, MHS
Assistant Professor of Oncology
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University
Bloomberg-Kimmel Institute for Cancer Immunotherapy
November 18, 2021
Lippard Lecture: Endometrial Cancer: Genetic Models & Translational Studies
Diego Castrillon, MD, PhD
Professor
Vernie A. Stembridge, MD, Distinguished Chair in Pathology
UT Southwestern Medical Center
December 2, 2021
Hot Topic Debate: Is Disease-Free Survival an Acceptable Surrogate Endpoint for Emerging Adjuvant TKI/IO Studies in NSCLC?
Justin Gainor, MD
Associate Professor of Medicine
Harvard Medical School
Massachusetts General Hospital
Rebecca Heist, MD, MPH
Associate Professor of Medicine
Harvard Medical School
Massachusetts General Hospital
Zofia Piotrowska, MD
Assistant Professor, Medicine
Harvard Medical School
Assistant in Medicine, Medicine
Massachusetts General Hospital
December 9, 2021
Disrupting the Paradigm in Cancer Research: Bringing the Patient into the P-Value
Jill Feldman
Group Founder, EGFR Resisters
Oncology Advances in Motion
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Krantz Family Center for Cancer Research
The scientific engine for discovery for the Mass General Cancer Center.
Grand Rounds
Mass General Cancer Center Grand Rounds is a CME accredited weekly seminar series. Cutting edge topics, case studies and conference highlights will be presented.